Products and Services » Diagnostics DiagnosticsPROMETHEUS® diagnostic services provide important information to help in the diagnosis and treatment of diseases. Test results should be used with other clinical findings to help physicians make a confirmed diagnosis.
PROMETHEUS® IBS Diagnostic is the first blood-based biomarker test for IBS, using Smart Diagnostic Algorithm technology to improve predictive accuracy. The test assesses 10 biomarkers for IBS providing clear, simple test results to complement the health care professional's clinical evaluation. The results can validate other diagnostic findings to help guide treatment decisions. For more information on IBS Diagnostic, please go to www.IBSbloodtest.com. The PROMETHEUS IBS Diagnostic is not currently available to residents of New York State.
PROMETHEUS® IBD Serology 7 is a test to help your physician determine if you have Inflammatory Bowel Disease (IBD), and if so, which type: ulcerative colitis or Crohn’s disease. Test results may provide your physician with prognostic and other useful information, and help determine the best course of treatment.
PROMETHEUS® Celiac PLUS is the most comprehensive serologic and genetics test for celiac disease. It includes both: PROMETHEUS® Celiac Genetics and PROMETHEUS® Celiac Serology PROMETHEUS® Celiac Genetics is a test that analyzes your genetic profile for certain genes (HLA DQ2 and HLA DQ8) associated with celiac disease. The result can predict with a 95%-100% chance that you do not have celiac disease. It could also show that you are very unlikely to ever develop the disease. Alternatively, the results may show that you do have genes associated with celiac disease and that you are at increased risk of developing symptoms, even if your serology (antibody) test is negative. PROMETHEUS® Celiac Serology is a test to measure specific antibody levels in your body that are associated with active celiac disease. If the levels are high, celiac disease is likely. For patients with celiac disease, these antibody levels should drop over time once patients remove gluten from their diet. This test may help your physician to diagnose celiac disease and monitor your compliance to a gluten-free diet.
PROMETHEUS® Thiopurine Metabolites is a test to monitor thiopurine medications. Because everyone metabolizes medications differently, your doctor may order this test to make sure your level of treatment is within a range that may help control symptoms. PROMETHEUS® TPMT Genetics is a test to determine the presence of genetic mutations associated with a decreased production of the thiopurine methyltransferase (TPMT) enzyme. This enzyme is responsible for the metabolism of a class of thiopurine drugs. Knowing the TPMT genotype allows your physician to individualize your dosing, and help identify patients who should not take these medications. PROMETHEUS® TPMT Enzyme is a test to determine the amount of thiopurine methyltransferase (TPMT) enzyme in your red blood cells. This enzyme is responsible for the metabolism of a class of thiopurine drugs. Knowing the TPMT enzyme levels allows your physician to individualize your dosing, and helps identify patients who should not take these medications.
PROMETHEUS® FIBROSpect® II is a test for patients diagnosed with hepatitis C who are at risk for developing liver fibrosis. This test uses a combination of protein markers to help predict the presence or absence of liver fibrosis and/or cirrhosis. This test is useful for initial patient evaluations and may help reduce the number of liver biopsies. PROMETHEUS® Serum Infliximab/ HACA Measurement is a test to detect human anti-chimeric antibodies (HACA) that may develop after receiving infliximab infusions. Patients who develop these antibodies at higher levels are at a greater risk of having complications from future infliximab infusions. Also, patients with higher antibody levels may have a shorter duration of benefit from the infliximab. PROMETHEUS® Serum Infliximab levels may be helpful to your physician in determining the dose and frequency of your infliximab infusions. PROMETHEUS® LactoTYPE® is a test used to identify a genetic variant that is strongly associated with the reduced production of lactase in adults. Lactase is an enzyme necessary for the digestion of the sugar lactose found in dairy products. Patients with this genetic variant typically have sensitivity to dairy products and are often diagnosed with lactose intolerance. Alternatively, patients with diagnosed lactose intolerance who do not have this genetic variant may have other underlying causes for their symptoms. PROMETHEUS® NOD2/CARD15 is a test to evaluate certain genetic variants for patients diagnosed with Crohn’s disease. Detection of one or more NOD2/CARD15 genetic mutations suggests a risk of having more severe symptoms and complications of the disease. This test is used to help establish a prognosis that may help guide treatment decisions by you and your doctor. BreathTek™ UBT is a breath test to detect the presence of Helicobacter pylori—a bacteria that can live in your stomach and is associated with peptic ulcer disease and stomach cancer.
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Celiac Diagnostics Patient Information Brochure
